This course takes e-commerce and blockchain applications as the two major themes, explaining the basic knowledge system and framework of e-commerce, the concept and application of blockchain, which includes e-commerce platform, modern logistics, WeChat and community, Cashless society, blockchain and remittance, degree accreditation, financial risk regulation, commodity traceability, etc.Starting from Tmall and Taobao, the representative e-commerce platforms of China, the operation and development status of China's online shopping mall platforms are described. The current continuous development of e-commerce has provided the modern logistics industry with an opportunity for rapid expansion. In addition, the popularization of social software and payment platforms represented by WeChat and Alipay has significantly increased people's living standards, and society has gradually developed towards a cashless trend.The course also discusses blockchain features such as centerless, encryption, smart contract, and non-deletability, and uses degree certification, risk monitoring, traceability, etc. as examples to illustrate the application scenarios of blockchain.